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Document and Entity Information Document Type Document Period End Date Current Fiscal Year End Date Entity Registrant Name Document Fiscal Year Focus Document Fiscal Period Focus Entity Central Index Key Amendment Flag Condensed Consolidated Statement of Financial Position Assets [abstract] Assets Property, plant and equipment including right-of-use assets Property, plant and equipment Non-current assets Non-current assets Cash and cash equivalents Cash and cash equivalents at the end of the period Cash and cash equivalents at beginning of the period Cash and cash equivalents Trade and other current receivables Trade and other receivables Total Current receivables from taxes other than income tax Other taxes Current assets Current assets Assets Total assets Equity and liabilities [abstract] Equity and liabilities Equity [abstract] Equity Equity attributable to owners of parent Equity attributable to owners of the Company Equity Balance at end of period Balance at beginning of period Total equity Liabilities [abstract] Liabilities Non-current lease liabilities Lease liabilities Non-current deferred income including non-current contract liabilities Deferred income Non-current deferred income Non-current liabilities Non-current liabilities Current borrowings and current portion of non-current borrowings Borrowings Current portion Current lease liabilities Lease liabilities Current derivative financial liabilities Derivative financial instruments Trade and other current payables Trade payables Current deferred income including current contract liabilities Deferred income Current deferred income Other current liabilities. Other current liabilities Current liabilities Current liabilities Liabilities Total liabilities Equity and liabilities Total equity and liabilities Condensed Consolidated Statement of Profit or Loss and Other Comprehensive Income Revenue from contracts with customers Revenue Other income. Total other income Other income Research and development expense Research and development costs Research and development costs General and administrative expense General and administrative costs General and administrative expense Operating expense Total operating costs Profit (loss) from operating activities Operating result Finance income (cost) Financial income and expense Gains (losses) on financial liabilities at fair value through profit or loss Results related to financial liabilities measured at fair value through profit or loss Profit (loss) before tax Result before corporate income taxes Profit (loss) Result for the period Result for the period Net result Other comprehensive income, net of tax, exchange differences on translation of foreign operations Other comprehensive income (foreign exchange differences on foreign operation) Comprehensive income Total comprehensive loss Profit (loss), attributable to [abstract] Result attributable to Profit (loss), attributable to owners of parent Owners of the Company Comprehensive income attributable to [abstract] Total comprehensive loss attributable to Comprehensive income, attributable to owners of parent Owners of the Company Weighted average ordinary shares used in calculating basic and diluted earnings per share [abstract] Share information Weighted average number of ordinary shares used in calculating basic earnings per share Weighted average number of shares outstanding (basic) Weighted average number of ordinary shares used in calculating diluted earnings per share Weighted average number of shares outstanding (diluted) Earnings Per Share Earnings per share attributable to owners of the Company (Euro per share) Basic earnings (loss) per share Basic loss per share Diluted earnings (loss) per share Diluted loss per share Condensed Consolidated Statement of Changes in Equity Statement of changes in equity [table] Components of equity [axis] Components of equity [domain] Issued capital [member] Share Capital Share premium [member] Share Premium Reserve of share-based payments [member] Equity Settled Employee Benefit Reserve Reserve of exchange differences on translation [member] Translation Reserve Retained earnings [member] Accumulated Deficit Statement of changes in equity [line items] Consolidated Statement of Changes in Equity Number of shares outstanding Balance at end of period (in shares) Balance at beginning of period (in shares) Other comprehensive income Other comprehensive income Increase (decrease) through share-based payment transactions, equity Recognition of share-based payments Number of treasury shares transferred during the period. Treasury Shares Transferred Treasury shares transferred (in shares) The increase (decrease) in equity resulting from share options lapsing Shares Options Lapsed Share options lapsed Increase (decrease) through exercise of options, equity Share options exercised / RSUs vested Number of shares issued during the period through the exercise of options IFRS Stock Issued During Period Shares Stock Options Exercised Share options exercised / RSUs vested (in shares) Condensed Consolidated Statement of Cash Flows Cash flows from (used in) operating activities [abstract] Cash flows from operating activities Adjustments to reconcile profit (loss) [abstract] Adjustments for: Adjustments for other income to reconcile profit (loss) to net cash flow from (used in) operating activities. Adjustments For Other Income Other income Adjustments for depreciation expense Depreciation Adjustments for share-based payments Share-based compensation Adjustments for finance income (cost) Financial income and expenses Adjustments for fair value losses (gains) Results related to financial liabilities measured at fair value through profit or loss Increase (decrease) in working capital Changes in working capital Cash flows from (used in) operations Cash used in operations Interest received, classified as operating activities Interest received Interest paid, classified as operating activities Interest paid Cash flows from (used in) operating activities Net cash used in operating activities Cash flows from (used in) investing activities [abstract] Cash flow from investing activities Purchase of property, plant and equipment, classified as investing activities Purchases of property, plant and equipment Cash flows from (used in) investing activities Net cash used in investing activities Cash flows from (used in) financing activities [abstract] Cash flow from financing activities Proceeds from exercise of options Proceeds from exercise of share options Payments of lease liabilities, classified as financing activities Repayment of lease liability Cash flows from (used in) financing activities Net cash used in financing activities Increase (decrease) in cash and cash equivalents before effect of exchange rate changes Net decrease in cash and cash equivalents Effect of exchange rate changes on cash and cash equivalents Currency effect cash and cash equivalents General Information [Abstract] General Information Disclosure of general information about the entity. Disclosure Of General Information Explanatory General Information n.a. Significant Accounting Policies Disclosure of material accounting policy information [text block] Significant Accounting Policies Adoption of New and Revised International Financial Reporting Standards Disclosure of initial application of standards or interpretations [text block] Adoption of New and Revised International Financial Reporting Standards Critical Accounting Estimates and Judgements Disclosure of accounting judgements and estimates [text block] Critical Accounting Estimates and Judgements Cash and Cash Equivalents. Disclosure of cash and cash equivalents [text block] Cash and Cash Equivalents Trade and Other Receivables. Disclosure of trade and other receivables [text block] Trade and Other Receivables Property, Plant and Equipment. Disclosure of property, plant and equipment [text block] Property, Plant and Equipment Other current liabilities. Other Current Liabilities Disclosure of other current liabilities [text block] Other Current Liabilities Borrowings. Disclosure of borrowings [text block] Borrowings Lease Liabilities Disclosure of leases [text block] Leases Liabilities No definition available. Deferred Income Disclosure of deferred income [text block] Deferred Income Shareholders' Equity Disclosure of share capital, reserves and other equity interest [text block] Shareholders' Equity Revenue. Disclosure of revenue [text block] Revenue No definition available. Other Income Disclosure of other operating income [text block] Other Income Research and development costs Research and Development Costs Disclosure of research and development expense [text block] Research and Development Costs General and Administrative Costs Disclosure of general and administrative expense [text block] General and Administrative Costs Investments in financial assets Investments in Financial Assets Disclosure of financial assets [text block] Investments in Financial Assets Income Taxes Disclosure of income tax [text block] Income Taxes Related-Party Transactions Disclosure of related party [text block] Related-Party Transactions Events After Balance Sheet Date Disclosure of events after reporting period [text block] Events After Balance Sheet Date Description of accounting policy for recognition of revenue [text block] Revenue Description of accounting policy for research and development expense [text block] Research and development expenditures Disclosure of going concern [text block] Going concern Tabular disclosure of trade and other receivables. Disclosure of trade and other receivables [table text block] Schedule of trade and other receivables Disclosure of detailed information about borrowings [text block] Schedule of borrowings Tabular disclosure of deferred income. Schedule of Deferred Income [Table Text Block] Summary of deferred income Tabular disclosure of other income. Disclosure Of Other Income Table Text Block Explanatory Schedule of other income Disclosure of subsidiaries [table] Subsidiaries [axis] Subsidiaries [domain] ProQR Therapeutics Holding B.V. [Member] ProQR Therapeutics Holding B.V. [Member] ProQR Therapeutics Holding B.V. ProQR Therapeutics I B.V. [Member] ProQR Therapeutics I B.V. [Member] ProQR Therapeutics I B.V. ProQR Therapeutics II B.V. [Member] ProQR Therapeutics II B.V. [Member] ProQR Therapeutics II B.V. ProQR Therapeutics III B.V. [Member] ProQR Therapeutics III B.V. [Member] ProQR Therapeutics III B.V. ProQR Therapeutics IV B.V. [Member] ProQR Therapeutics IV B.V. [Member] ProQR Therapeutics IV B.V. ProQR Therapeutics V B.V. [member] ProQR Therapeutics V B.V. [Member] ProQR Therapeutics V B.V. ProQR Therapeutics VI B.V. [Member] ProQR Therapeutics VI B.V. [Member] ProQR Therapeutics VI B.V. ProQR Therapeutics VII B.V. [Member] ProQR Therapeutics VII B.V. [Member] ProQR Therapeutics VII B.V. ProQR Therapeutics VIII B.V. [Member] ProQR Therapeutics VIII B.V. [Member] ProQR Therapeutics VIII B.V. ProQR Therapeutics IX B.V. [Member] ProQR Therapeutics IX B.V. [Member] ProQR Therapeutics IX B.V. ProQR Therapeutics I Inc. [Member] ProQR Therapeutics I Inc. [Member] ProQR Therapeutics I Inc. Disclosure of subsidiaries [line items] Proportion of ownership interest in subsidiary Proportion of ownership interest in subsidiary Disclosure of temporary difference, unused tax losses and unused tax credits [table] Disclosure of temporary difference, unused tax losses and unused tax credits [line items] Number of segments reported by the entity. A reportable segment is a component of an entity for which there is an accounting requirement to report separate financial information on that component in the entity's financial statements. Ifrs Number of Reportable Segments Number of reportable segment Disclosure of disaggregation of revenue from contracts with customers [table] Counterparties [axis] Counterparties [domain] Eli Lilly and Company. Eli Lilly and Company Eli Lilly and Company Disclosure of disaggregation of revenue from contracts with customers [line items] Deferred income including contract liabilities Deferred income Total deferred income Current receivables from collaboration agreements. Current receivables from collaboration agreements Collaboration receivables Current prepayments Prepayments Current accrued income including current contract assets Accrued income from Rett Syndrome Research Trust Other current receivables Other receivables Disclosure of detailed information about property, plant and equipment [table] Classes of property, plant and equipment [axis] Classes of property, plant and equipment [domain] Leasehold improvements [member] Buildings and Leasehold improvements Disclosure of detailed information about property, plant and equipment [line items] Property, Plant and Equipment Right-of-use assets Right-of-use asset Disclosure of detailed information about borrowings [table] Borrowings by name [axis] Borrowings by name [domain] Represents the information pertaining to innovation credit. Innovation credit Innovation credit Classes Of Warrants Or Rights Axis IFRS Classes Of Warrants Or Rights Axis [Axis] Classes of warrants or rights Classes of warrants or rights [Domain] This member represents the Pontifax and Kreos warrants. Pontifax and Kreos warrants [Member] Pontifax and Kreos warrants Disclosure of detailed information about borrowings [line items] Borrowings Total Interest payable Accrued interest on innovation credit Notional amount Notional amount Repayments of borrowings, classified as financing activities Repayment of borrowings Current borrowings excluding accrued interest Current borrowings excluding accrued interest The total amount of debt including interest can be waived up on satisfying the conditions. Conditional Waiver of Debt, Total Total conditional waiver of debt Warrants, economic lifetime Warrants, economic lifetime Warrants, economic lifetime Disclosure of quantitative information about right-of-use assets [table] This member stands for office and laboratory space. Office and Laboratory Facility [Member] Office and Laboratory Facility Geographical areas [axis]